With hepatic activity typically associated with an enlarged liver. Liver to make up for their lack of functionality hypertrophy, thus increasing its volume, which is a common symptom of a malfunction or overload. Liver besides numerous metabolic functions stored animal starch glycogen, which is the first storage substance, which is easily applicable in a period between meals. Therefore, liver may shrink during malnutrition, which does not form enough storage compounds which are liver continuously stored. The liver can also reduce at large failure and necrosis of the liver tissue.

Internal tests help detect liver damage. Because the liver is an important metabolic organ of the body, it is necessary to start their treatment as soon as possible in order not permanently damaged.